The Sodium Citrate + Biotin PRP tube is a sterile blood collection tube specially designed for the preparation of Platelet-Rich Plasma (PRP). It contains two key components: sodium citrate as an anticoagulant and biotin (vitamin B7) as a regenerative co-factor. This combination supports PRP preparation for skin rejuvenation, tissue repair, and especially hair restoration applications.
By incorporating both anticoagulant and nutritional functions, this PRP tube offers enhanced biological activity and cell viability, making it a preferred choice in aesthetic medicine, particularly for hair loss therapies.
Ingredient Analysis: Science Behind Anticoagulation and Nutritional Support
1. Sodium Citrate – Ensures Blood Stability
During PRP preparation, anticoagulation is essential to prevent clotting. Sodium citrate works by chelating calcium ions in the blood, effectively inhibiting the coagulation cascade and allowing for efficient plasma separation.
Compared with EDTA or heparin, sodium citrate has minimal impact on platelet activity and does not interfere with the release of growth factors. This makes it a highly suitable anticoagulant for regenerative therapies.
2. Biotin – Stimulates Follicular Metabolism
Biotin, also known as vitamin B7, is a water-soluble vitamin crucial for cellular metabolism and keratin production. It supports healthy hair, skin, and nails.
Incorporating biotin into the PRP tube helps enhance the regenerative capacity of the prepared plasma. It works synergistically with growth factors in PRP to:
- Stimulate the proliferation of follicular stem cells;
- Promote keratin protein synthesis;
- Activate signaling pathways such as TGF-β and VEGF;
- Extend the anagen (growth) phase and shorten the telogen (resting) phase.
This dual approach—plasma-based repair combined with nutritional activation—makes the tube particularly effective for scalp injection treatments.
Clinical Value in Hair Loss Treatment
Hair loss, especially non-scarring types such as androgenetic alopecia (AGA), alopecia areata, and postpartum shedding, is a growing concern in both dermatology and aesthetic medicine. Sodium Citrate + Biotin PRP tubes offer targeted benefits for these conditions by:
- Delivering growth factors and biotin directly to the follicle roots;
- Reducing microinflammation around the hair follicles;
- Reactivating dormant follicles and improving density;
- Enhancing the effects of adjunct therapies, such as minoxidil or low-level laser therapy (LLLT).
Most treatment protocols involve 1 session per month for 3–6 months. Visible improvements often appear after 2–3 sessions, with progressive thickening and new hair growth during follow-up.
Standard Procedure and Usage
To ensure optimal results, PRP collection and injection should be performed by trained professionals under sterile conditions. The typical workflow includes:
- Blood Collection – Draw 8–10ml of venous blood into the Sodium Citrate + Biotin PRP tube.
- Centrifugation – Spin at recommended speed (e.g., 3500 rpm for 10 minutes) to separate plasma layers.
- PRP Extraction – Use a pipette to collect the platelet-rich plasma layer while avoiding red blood cell contamination.
- Injection – Administer PRP into the scalp using point injection, micro-needling, or a grid pattern technique.
- Post-treatment Care – Advise patients to avoid shampooing and alcohol-based scalp products for 24 hours.
To boost results, the therapy may be combined with microneedling, phototherapy, or oral supplements.
Comparison with Other PRP Tubes
The Sodium Citrate + Biotin PRP tube stands out from conventional PRP tubes by offering both anticoagulant stability and targeted nutritional enhancement for hair loss therapies. Below is a comparison with common alternatives:
Compared with ACD PRP Tubes
ACD tubes are widely used for general PRP applications. While effective in anticoagulation, their chemical content may irritate sensitive patients and potentially interfere with metabolic activity. Sodium citrate offers a milder anticoagulation process that helps preserve the bioactivity of key growth factors, especially important in aesthetic and hair treatments.
Compared with EDTA PRP Tubes
EDTA is a strong anticoagulant commonly used in laboratory diagnostics. However, it may negatively affect protein structures or platelet membrane integrity. In contrast, sodium citrate maintains platelet function and results in a cleaner PRP layer with higher regenerative value—ideal for hair follicle therapies.
Compared with Non-Additive Tubes
Plain tubes without additives may risk premature clotting and reduced plasma yield, especially in field or busy clinic settings. In comparison, Sodium Citrate + Biotin tubes prevent coagulation and offer enhanced PRP functionality thanks to biotin’s regenerative support.
Compared with Gel-Containing Tubes
Some PRP tubes include separation gel to help isolate the plasma. However, concerns have been raised about gel residues interfering with PRP purity and tissue compatibility. Our tube features a gel-free design, ensuring a purer plasma fraction, making it especially suitable for sensitive areas like the scalp and dermis.
Suitable Candidates and Precautions
Recommended for:
- Male patients with early- to mid-stage androgenetic alopecia;
- Women experiencing postpartum or hormonal hair loss;
- Patients with alopecia areata or stress-induced shedding;
- Individuals seeking to improve hair density, texture, and strength.
Not recommended for:
- Patients with autoimmune conditions like lupus;
- Individuals with bleeding disorders or severe anemia;
- People with known biotin hypersensitivity (very rare);
- Patients on active anticoagulant therapy.
FQAs
Q1: Does biotin interfere with PRP concentration?
A1: No. Biotin does not affect platelet separation or count. Instead, it enhances the biological activity of the resulting PRP by supporting cell metabolism and tissue repair.
Q2: Can it be used for female hair loss?
A2: Absolutely. It’s particularly beneficial for women with postpartum or hormonally related thinning.
Q3: When will the results become visible?
A3: Most patients begin to notice early signs of regrowth—such as fine vellus hairs—after 2–3 sessions. Full results typically appear after 3–6 months.
Q4: Are there any side effects?
A4: When performed correctly, PRP therapy is very safe. Minor redness or itching at the injection site may occur, but usually resolves within 24 hours.
Summary
The Sodium Citrate + Biotin PRP tube combines safe anticoagulation with follicle-focused nutritional enhancement, making it a powerful tool for modern hair restoration therapies. Whether in clinical dermatology or aesthetic practices, this tube offers precision, purity, and performance. Selecting the right PRP tube is a crucial step in achieving consistent treatment results and patient satisfaction.
For detailed specifications, OEM inquiries, or clinical usage support, please do not hesitate to contact us SinyPRP Website and the Sinymedical Website.