I-PRF, short for Injectable Platelet-Rich Fibrin, is a biological material derived from a patient’s blood. After specific processing, it exists in a liquid form, making it easier to accurately inject into the treatment site. I-PRF is an improvement over traditional PRF and aims to enhance the precision and convenience of treatment.
Compared to traditional PRF, iPRF undergoes additional processing steps during extraction to transform PRF into a liquid form, facilitating its use with injectors. This liquid form makes iPRF more suitable for treatment scenarios requiring precise injection, such as repairing soft tissue injuries, intra-articular injections to promote joint healing and skin regeneration therapy.
iPRF still contains the same biological active components as PRF, including platelets, white blood cells, growth factors, and cytokines, Contributing to tissue repair and regeneration.
PRF vs I-PRF
PRF is a biological material derived from a patient’s blood. We extract it through a specific preparation process, which results in a product primarily containing platelets, white blood cells, growth factors, and cytokines, along with other biologically active components.
Extraction Method:
In blood collection, we draw a certain amount of blood from the patient’s vein, usually using tubes that contain anticoagulants. Next, we place the collected blood in a centrifuge and spin it at specific parameters to separate it into distinct layers. This process yields a fibrin gel layer rich in platelets and white blood cells.
PRF Extraction: The fibrin gel layer rich in platelets and white blood cells is extracted from the blood after centrifugation, referred to as PRF.
Application: PRF finds wide applications in various medical fields, including dentistry, plastic surgery, and dermatology. We can use it for socket preservation, soft tissue healing after dental implant placement, skin regeneration, and various other treatments.
I-PRF (Injectable Platelet-Rich Fibrin)
I-PRF is an improved form of PRF that exists in a liquid form, making it easier to inject into the treatment site accurately. It also comes from the patient’s blood and contains biologically active components similar to PRF ones.
Extraction Method:
In blood collection for iPRF, we collect blood from the patient’s vein, just as we do for PRF.
Centrifugation and Layering: After centrifugation, the collected blood undergoes layering similar to PRF. In the preparation process of iPRF, we further process PRF into a liquid form through a series of steps. This liquid processing involves converting PRF into a liquid using methods like heating, stirring, or filtration to make it suitable for use with injectors.
Application: iPRF is suitable for treatments requiring precise injection, such as repairing soft tissue injuries, and intra-articular injections to promote joint healing and skin regeneration therapy.
Compare the advantages of PRF and I-PRF
PRF Features and Advantages:
Gel state, suitable for filling and covering surgical sites.
Rich in growth factors, promoting angiogenesis and tissue regeneration.
Widely used in dentistry, plastic surgery, and dermatology.
I-PRF Features and Advantages:
Liquid state, facilitating accurate injection into target tissues.
Similarly, it is rich in growth factors, promoting tissue repair and regeneration.
Simple to operate, with no need for additional filling or curing steps.
Conclusion
PRF and iPRF differ in their extraction methods and applications, but they both derive from a patient’s blood and contain similar biologically active components that play crucial roles in tissue repair and regeneration. The choice between the two depends on the treatment needs, surgical complexity, and characteristics of the treatment site.