Siny Medical 5ml Formalin Solution Tissue Fixative in Histopathology

The 5ml Formalin Solution Tissue Fixative is designed for clinical pathology, scientific research, and educational use. It uses high-purity formaldehyde processed with modern techniques to quickly fix biopsy samples, surgical specimens, and research tissues. This fixative protects cell structures and molecular components, providing a solid basis for staining, sectioning, and pathological analysis. Its efficiency, stability, and safety make it a top choice for hospitals, laboratories, and research institutions.

Product Features and Advantages

• Efficient Fixation

Formaldehyde reacts with tissue proteins to form cross-links that quickly stabilize cell structures. This process preserves the nucleus, cytoplasm, and extracellular matrix, while also preventing enzymatic degradation and microbial contamination.

• Excellent Tissue Integrity

The fixative preserves detailed cellular structures so that cell shapes and nucleoli remain clear, helping pathologists achieve accurate diagnoses. It also maintains key molecules for immunohistochemistry and molecular testing.

• Simple Operation and Precise Control

The 5ml size allows for accurate measurement and easy handling. Users can adjust the fixation time based on tissue size and density to achieve optimal results.

• Strict Quality Control

The product meets both national and international medical device standards. Each batch undergoes rigorous sterility and stability tests to ensure consistent quality and reliable performance.

Applications

• Clinical Pathology

Ideal for fixing biopsy samples, surgical specimens, and challenging cases. It provides high-quality tissue for accurate diagnosis.

• Scientific Research and Drug Development

Widely used in molecular biology, pathology, and pharmacology experiments. It helps maintain tissue structure and molecular information for reliable research outcomes.

• Medical Education

Commonly used in pathology and histology courses, it assists students in understanding the principles of tissue fixation and staining.

Scientific Basis

The main ingredient, formaldehyde, reacts with tissue proteins to form covalent cross-links that “freeze” cell structures. This reaction not only preserves cell morphology but also protects nucleic acids and enzymes from degradation. The cross-links resist heat and enzymes, which is crucial for dehydration, embedding, and staining processes. Adjusting the fixation time and ratio balances tissue preservation with optimal staining quality.

Usage Instructions and Operation Guide

1. Sample Preparation
   • Collect tissue samples carefully to avoid damage.
   • Immediately immerse the sample in the prepared 5 mL formalin solution to prevent degradation or contamination.
2. Fixation Ratio and Time Control
   • Maintain a fixative-to-tissue volume ratio of about 10:1 for complete penetration.
   • Small or thin tissues usually need 4 to 6 hours of fixation; larger or denser tissues may require 12 to 24 hours. Over-fixation can affect staining quality.
3. Post-Fixation Processing
   • After fixation, promptly move to dehydration, clearing, and paraffin embedding to maintain tissue quality.
   • Timely processing helps prevent tissue hardening.

Precautions and Safety Measures

• Personal Protection

Always wear gloves, goggles, and a mask when handling the product to avoid skin contact and inhaling formaldehyde vapors.

• Environmental Requirements

Use the fixative in a well-ventilated area. Avoid enclosed spaces to minimize exposure to fumes.

• Chemical Compatibility

Do not mix the fixative with strong acids, bases, or other reactive chemicals to prevent hazardous reactions.

• Storage

Store the product in a cool, dry, ventilated place away from direct sunlight and high temperatures. Seal the container after use to prevent contamination and degradation.

Quality Assurance and Service Commitment

We manufacture this fixative following strict national and international standards. Each batch undergoes comprehensive tests for sterility, stability, and safety. Our dedicated technical support team stands ready to assist with any questions or issues, ensuring a smooth and reliable experience with our product.

Final Thoughts

The 5ml Formalin Solution Tissue Fixative delivers excellent fixation, consistent quality, and ease of use. It supports accurate tissue pathology and research by preserving cell structures and molecular components. This product plays a key role in clinical diagnosis, scientific research, and medical education. We remain committed to innovation, quality, and exceptional service to advance global healthcare and research. Choose this fixative to ensure reliable results and a smooth workflow in your practice.